The most authorititive, in-depth wok on biomedical physics ever published.

Table of Contents

• Editorial Board
• Preface
• Permissions Acknowledgement
• Volume 1 Nuclear Medicine and Molecular Imaging
• Introduction
• History of Nuclear Medicine and Molecular Imaging
• Single-Photon Radionuclide Imaging and SPECT
• Dynamic Single-Photon Emission Computed Tomography
• Scatter Correction in SPECT
• Compton Emission Tomography
• Positron Emission Tomography
• Time-of-Flight Positron Emission Tomography
• Time-of-Flight PET Reconstruction Strategies
• Positron Emission Tomography (PET)/Computer Tomography (CT)
• High-Resolution Small Animal Imaging
• Emission Tomography Motion Compensation
• Tracer Kinetic Models in PET
• Absorbed Radiation Dose Assessment from Radionuclides
• Volume 2 X-Ray and Ultrasound Imaging
• Introduction
• Physical Basis of x-Ray Imaging
• Physical Parameters of Image Quality
• Computed Tomography
• Oral and Maxillofacial Radiology
• Breast Imaging
• Dual-Energy and Spectral Imaging
• Quality Controls in x-Ray Imaging
• x-Ray Imaging with Coherent Sources
• High-Resolution CT for Small-Animal Imaging Research
• Radiation Protection and Dosimetry in x-Ray Imaging
• Fundamentals of CT Reconstruction in 2D and 3D
• The Basics of Ultrasound
• Ultrasound Imaging Arrays
• Doppler Ultrasound
• Ultrasound Imaging Modalities
• Nonlinear Acoustics
• Biomedical Applications of Ultrasound
• Biological Effects in Diagnostic Ultrasound
• Simulation of Ultrasound Fields
• Ultrasound Research Platforms
• Volume 3 Magnetic Resonance Imaging and Spectroscopy
• Introduction
• Fundamentals of MR Imaging
• Image Contrast and Resolution in MRI
• Perfusion Imaging and Hyperpolarized Agents for MRI
• High Versus Low Static Magnetic Fields in MRI
• Functional Magnetic Resonance Imaging (fMRI)
• Diffusion-Weighted MRI
• MRI of the Brain
• MRI of the Cardiovascular System
• MRI of the Liver
• MRI of the Pancreas and Kidney
• MRI of the Small and Large Bowel
• MR Imaging of the Prostate
• MRI of the Breast
• MRI of the Female Genitourinary Tract
• Three-Dimensional Multispectral MRI for Patients with Metal Implants
• Fundamentals of MR Spectroscopy
• Magnetic Resonance Spectroscopy (MRS) of the Brain
• MR Spectroscopy (MRS) of the Prostate
• MRS of the Breast
• Potential and Obstacles of MRS in the Clinical Setting
• Magnetic Resonance Spectroscopic Imaging
• Clinical Applications of Magnetic Resonance Spectroscopic Imaging
• In Vivo Two-Dimensional Magnetic Resonance Spectroscopy
• Basic Science Input into Clinical MR Modalities
• Mathematically Optimized MR Reconstructions
• Interdisciplinarity of MR and Future Perspectives with a Focus on Screening
• Volume 4 Optical Molecular Imaging
• Introduction
• Bio-optical Imaging
• Signal-Relevant Properties of Fluorescent Labels and Optical Probes and Their Determination
• Fluorescent Proteins
• Fluorescent Nanoparticles
• Molecular Imaging Probes: Activatable and Sensing Probes
• Fluorescence Resonance Energy Transfer Probes
• Multimodal Optical Imaging Probes
• Fluorescent Reporters and Optical Probes
• Advanced Fluorescence Microscopy
• Uncovering Tumor Biology by Intravital Microscopy
• Two-Photon Microscopy
• Optical Frequency-Domain Imaging
• Raman-Based Technologies for Biomedical Diagnostics
• Optical Coherence Tomography
• Two-Dimensional In Vivo Fluorescence Imaging
• Bioluminescence Imaging
• Inverse Models for Diffuse Optical Molecular Tomography
• Hybrid Optical Imaging
• Optoacoustic Imaging
• Fluorescence-Guided Surgery: A Promising Approach for Future Oncologic Surgery
• Confocal Laser Endomicroscopy Applications
• Optical Imaging in Mammography
• External Transdermal Procedures
• High Content Screening and Analysis with Nanotechnologies
• Volume 5 Physics of Physiological Measurements
• Introduction
• Electrical Activities in the Body
• Electrocardiography
• Bioelectric Measurements: Magnetoencephalography
• Tissue Impedance Spectroscopy and Impedance Imaging
• Blood Flow Measurement
• Measurement of Temperatures of the Human Body
• Force Measurements
• Smart Homes: Ambient Intelligence and How IT Can Help Increase Longevity
• Wearable Sensors
• Volume 6 Bioinformatics
• Introduction
• Artificial Neural Networks
• Learning Rule-Based Models - The Rough Set Approach
• Algorithms for Mapping High-Throughput DNA Sequences
• Text Mining
• Semantic Web, Ontologies, and Linked Data
• Nomenclature of Genes and Proteins
• Phylogenetic Analyses
• Computational Approaches for Predicting Mutation Effects on RNA Structure
• Chemoinformatics
• Lipidomics in Metabolomics
• Genome-Scale Metabolic Models: A Link between Bioinformatics and Systems Biology
• EBI and ELIXIR
• Databases and Datasources at SIB, Swiss Institute of Bioinformatics
• Volume 7 Radiation Biology and Radiation Safety
• Introduction
• Early Events Leading to Radiation-Induced Biological Effects
• Microbeam Radiation Biology
• Molecular Radiation Biology
• Cellular Radiation Biology
• Normal Tissue Radiobiology
• Tumor Radiation Biology
• Accurate Analytical Description of the Cell Survival and Dose-Response Relationships at Low and High Doses and LETs
• Genetic Susceptibility and Predictive Assays
• Genetic Effects and Risk Estimation
• Light Ion Radiation Biology
• Radiological Protection of Patients and Personnel
• Radiation Biology of Radiation Protection
• Radiation Biology of Tissue Radiosterilization
• Established and Emerging Methods of Biological Dosimetry
• Radiation and Environmental Protection
• Biological Effects and Health Consequences of ELF and RF Fields
• Volume 8 Radiation Sources and Detectors
• Introduction
• Electron Linear Accelerators
• Synchrotron Radiation
• Inverse Compton Scattering Sources
• Tabletop Synchrotron Light Source
• Free-Electron Laser Sources
• Petawatt Laser and Laser Ion/Electron Accelerator
• Electron-Impact Liquid-Metal-Jet Hard x-Ray Sources
• Laser-Impact Metal Droplet EUV Source
• x-Ray Free-Electron Lasers
• Ion Linac and Synchrotron
• FFAG
• Cyclotrons
• Neutron Sources
• Radionuclide Production
• Diamond Detectors for Dosimetry
• Scintillator-Based Detectors
• Active Pixel CMOS-Based Radiation Detectors
• CdTe Detectors
• Amorphous Silicon Detectors
• Selenium Detectors
• Silicon Photomultipliers
• Gas Electron Multiplier (GEM) Detectors: Principles of Operation and Applications
• Silicon Trackers
• Volume 9 Radiation Therapy Physics and Treatment Optimization
• Introduction
• Interaction of Ionizing Radiation with Matter
• Particle Transport Theory and Absorbed Dose
• Biophysical Basis of Ionizing Radiation
• Modeling of Radiation Effects in Cells and Tissues
• From Cell Survival to Dose-Response Relations for Organized Tissues
• Dose-Response Relations for Tumors and Normal Tissues
• Accurate Description of Heterogeneous Tumors by Their Effective Radiation-Sensitive and -Resistant Cell Compartments
• Tumor Hypoxia
• Long-Term Effects and Secondary Tumors
• Patient Dose Computation
• Convolutions and Deconvolutions in Radiation Dosimetry
• Fundamentals of Physically and Biologically Based Radiation Therapy Optimization
• Brachytherapy Physics
• Stereotactic Radiation Therapy Planning
• Modulated Arc Therapy Planning
• In-Room Image-Guided Radiation Therapy
• Intensity-Modulated Radiation Therapy Planning
• Adaptive Treatment Planning
• Light-Ion Radiation Therapy Planning
• Stereotactic Radiation Therapy
• Biologically Optimized Light Ion Therapy
• Volume 10 Physical Medicine and Rehabilitation
• Introduction
• Biomechanics of Musculoskeletal Adaptation
• Mechanics of Biofluids in Living Body
• Bioelectromagnetism in the Living Body
• Ion Channels in the Cell Membrane: Structure, Function, and Modeling
• Water Biology in Human Body
• Human Immune System
• Hyperthermia Therapy for Cancer
• Ultrasound Therapy
• Laser Surgery
• Photodynamic Techniques in Medicine
• Electro-Muscle Stimulation Therapy
• Defibrillation
• Electroporation Therapy
• Transcranial Magnetic Stimulation
• Biophysical Bases of Acupuncture
• Music Psychophysics and Therapy
• Medical Bionics
• Cold Plasma Therapy
• Smart-Drug Delivery and Target-Specific Therapy
• Orthopedic Physical Therapy
• Neurological Rehabilitation
• Pulmonary Rehabilitation
• Principles and Applications of Vestibular Rehabilitation