Following an overview of nanotechnologies for diagnostic purposes, this book goes on to look at nanoparticle-based magnetic resonance, molecular and other imaging applications, as well as the potential roles of carbon nanotubes and bionanoparticles in biomedical applications. The book's main focus is on drug delivery systems based on nonporous and nanosize materials, solid lipid and polymeric nanoparticles, intelligent hydrogels, core-shell nanoparticles, and nanocapsules, rounded off by a discussion of their biomedical applications. The final part of this volume covers such biomedical strategies as gene therapy, synthetic gene-transfer vectors and targeted delivery.

Table of Contents

• Foreword
• Preface
• List of Contributors
• 1 Nanotechnologies for Diagnosis - Present and Future - Gareth A. Hughes
• 2 Superparamagnetic Nanoparticles of Iron Oxides for Magnetic Resonance Imaging Applications - Jean-Marc Idee, Marc Port, Isabelle Raynal, Michel Schaefer, Bruno Bonnemain, Philippe Prigent, Philippe Robert, Caroline Robic, and Claire Corot
• 3 Carbon Nanotube-based Vectors for Delivering Immunotherapeutics and Drugs - Alberto Bianco, Wei Wu, Giorgio Pastorin, Cedric Klumpp, Lara Lacerda, Charalambos D. Partidos, Kostas Kostarelos, and Maurizio Prato
• 4 Core-Shell Nanoparticles for Drug Delivery and Molecular Imaging - Sung Kyun Han, Ree Sun Kim, Jin Ho Lee, Ciyoong Tae, Sun Hang Cho, and Soon Hong Yuk
• 5 Nanotechnologies for Targeted Delivery of Drugs - Pavel Broz and Patrick Hunziker
• 6 Nanoporous and Nanosize Materials for Drug Delivery Systems - Yoshinobu Fukumori, Kanji Takada and Hirofumi Takeuchi
• 7 NANOEGG® Technology for Drug Delivery - Yoko Yamaguchi and Rie Igarashi
• 8 Polymeric Nanomaterials - Synthesis, Functionalization and Applications in Diagnosis and Therapy - Yoko Yamaguchi and Rie Igarashi
• 9 Polymeric Nanoparticles for Drug Delivery - Paraskevi Kallinteri and Martin C. Carnett
• 10 Solid Lipid and Polymeric Nanoparticles for Drug Delivery - Jose Luis Pedraz, Corka Orive, Manoli Igartua, Alicia R. Gascon, Rosa M. Hernandez, Maria Angeles Solinis, and Amaia Esquisabel
• 11 Intelligent Hydrogels in Nanoscale Sensing and Drug Delivery Applications - J. Zach Hilt
• 12 Nanoshells for Drug Delivery - Melgardt M. De Villiers and Yuri Lvov
• 13 Bionanoparticles and their Biomedical Applications - L Andrew Lee, Hannah N. Barnhill, and Qian Wang
• 14 Nanotechnology for Gene Therapy - HVJ-E Vector - Hironori Nakagami, Yasuhiko Tabata, and Yasufumi Kaneda
• 15 Nanotoxicology of Synthetic Gene Transfer Vectors: Poly(ethyleneimine)- and Polyfectin-mediated Membrane Damage and Apoptosis in Human Cell Lines - Seyed M. Moghimi
• 16 Nanoparticles for the Treatment of Alzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives - Gang Liu, Ping Men, George Perry and Mark A. Smith