Molecular Life Sciences: An Encyclopedic Reference will focus on understanding biological phenomena at the level of molecules and their interactions that govern life processes.

Table of Contents

• Editors and Contributors
• A
• Adducts on Tm, Effects of
• Allostery and Quaternary Structure
• Artificial Chromosomes
• Artificial Endonucleases for Genome Editing
• B
• Bacterial DNA Replicases
• Bacteriophage and Viral Cloning Vectors
• Base Intercalation in DNA
• Bioactivation of Carcinogens
• Bioinorganic Chemistry
• Blue/White Selection
• C
• Chemical Denaturation
• Chemical Reaction Kinetics: Mathematical Underpinnings
• Chromatin Remodeling and DNA Modification in Transcriptional Regulation, Role of
• Chromatin Remodeling During Homologous Recombination Repair in Saccharomyces cerevisiae
• Cis-Regulation of Eukaryotic Transcription
• Cloning Vector Compatibility
• Complement System
• Conjugative Transfer Systems and Classifying Plasmid Genomes
• Conservative Site-Specific Recombination
• Control of Initiation in E. coli
• Co-transcriptional mRNA Processing in Eukaryotes
• Cycling of the Lagging Strand Replicase During Okazaki Fragment Synthesis
• Cytoplasmic mRNA, Regulation of
• D
• Damage DNA, Natural Products that
• Damaged DNA, Analysis of
• Depurination
• Differential Equations and Chemical Master Equation Models for Gene Regulatory Networks
• Direct Enzymatic Reversal of DNA Damage
• Division of Labor
• DNA Base Pairing, Modes of
• DNA Cross-Linking
• DNA Damage as a Therapeutic Strategy
• DNA Damage by Endogenous Chemicals
• DNA Damage, Frequency of
• DNA Damage, Practical Screening for
• DNA Damage, Relevance to Cancer
• DNA Damage, Types of
• DNA Methylation and Cancer
• DNA Polymerase III Structure
• DNA Recombination, Mechanisms of
• DNA Repair
• DNA Repair Polymerases
• DNA Replication
• DNA Replication, Chemical Biology of
• DNA Topology and Topoisomerases
• DnaA, DnaB, DnaC
• DnaX Complex Composition and Assembly Within Cells
• Double-Strand Break Repair
• DSB Repair by Cell-Cycle Signaling and the DNA Damage Response, Regulation of
• E
• Electrophiles, Types of
• End Joining, Classical and Alternative
• Enzymes and Cloning Vectors Used to Create Recombinant DNA, Characteristics of
• Epigenetic Research, Computational Methods in
• Equilibria and Bifurcations in the Molecular Biosciences
• Eukaryotic DNA Replicases
• Exocyclic Adducts
• Expression Assessment
• F
• Fatty Acid Metabolism
• G
• Gene Regulation
• Gene Regulatory Networks, Evolution of
• Genes and Genomes: Structure
• Genetic Element Mobility, Regulation of
• Genomic Imprinting
• Genomic Imprinting in Mammals: Memories of Generations Past
• Genomic Sequence and Structural Diversity in Plants
• Genomic Signature Analysis to Predict Plasmid Host Range
• Golgi Apparatus
• Gyrase and Topoisomerase IV as Targets for Antibacterial Drugs
• H
• HDAC Inhibitors Entinostat and Suberoylanilide Hydroxamic Acid (SAHA): The Ray of Hope for Cancer Therapy
• Helicase and Primase Interactions with Replisome Components and Accessory Factors
• Helicase Mechanism of Action
• Hereditary Breast and Ovarian Cancer and Poly(ADP-Ribose) Polymerase Inhibition
• Homologous Recombination in Lesion Bypass
• Hydrolytic, Deamination, and Rearrangement Reactions of DNA Adducts
• I
• Immunology and the Immune Response
• In Silico Approaches Towards Safe Targeting of Class I Histone Deacetylases
• Inflammation and Host Response to Infection
• Inflammation, Resolution of
• Initiation Complex Formation, Mechanism of
• Innate B Cells
• Innate Immunity
• Ion Channels and Transporters
• K
• Key Enzymes Used in Cloning, Some
• Kinetics of DNA Damage
• L
• Long-Term Genetic Silencing at Centromere and Telomeres
• M
• Mammalian Solute Carrier Families SLC2 and SLC5: Facilitative and Active Transport of Hexoses and Polyols
• Many Bacteria Use a Special Mutagenic Pol III in Place of Pol V
• Mass Spectrometry Approaches
• Mathematical Modeling of Plasmid Dynamics
• Mathematical Models in the Sciences
• Mathematics of Fitting Scientific Data
• Meiotic Recombination
• Metamobilomics – The Plasmid Metagenome of Natural Environments
• Mismatch Repair
• Mitochondrial Genomes
• Mitochondrial Genomes in Alveolates
• Mitochondrial Genomes in Amoebozoa
• Mitochondrial Genomes in Fungi
• Mitochondrial Genomes in Invertebrate Animals
• Mitochondrial Genomes in Land Plants
• Mitochondrial Genomes in Unicellular Relatives of Animals
• Mitochondrial Genomes in Vertebrate Animals
• Mitochondrial Genomes of Chromists (Stramenopiles, Haptophytes and Cryptophytes)
• Mitochondrial Genomes of Excavata
• Mitochondrial Genomes of Green, Red and Glaucophyte Algae
• Mobile DNA: Mechanisms, Utility, and Consequences
• mRNA Localization and Localized Translation
• N
• NMR Approaches to Determine Protein Structure
• NMR Basis for Biomolecular Structure (Theory)
• Non-allosteric Proteins. Why Do Proteins Have Quaternary Structure?
• Nuclear Lamin–Chromatin Interactions and Their Signaling Cascades
• Nucleotide Excision Repair
• O
• Obtaining Crystals
• Oxidative DNA Damage
• P
• Pattern Recognition Receptors: Evolution, Redundancy, and Cross Talk
• PCNA Loading by RFC, Mechanism of
• PCNA Structure and Interactions with Partner Proteins
• Peptide Pheromones and Their Protein Receptors: Cellular Signaling in Gram-Positive Bacteria
• Phagocytosis
• Plant Genome Annotation, Methods for
• Plant Genome Sequencing Methods
• Plant Genomes, Evolution of
• Plant Genomes: From Sequence to Function Across Evolutionary Time
• Plant Transposable Elements: Beyond Insertions and Interruptions
• Plasmid Cloning Vectors
• Plasmid Genomes, Introduction to
• Plasmid Incompatibility
• Plasmid Regulatory Systems, Modeling
• Plasmids as Secondary Chromosomes
• Plasmids, Naming and Annotation of
• Polyglutamine Folding Diseases
• Polymerase Chain Reaction
• Post-Translational Modifications in DNA Double Strand Break Repair, Roles of
• Predictions from Sequence
• Primary Structure
• Prokaryotic Gene Regulation by Sigma Factors and RNA Polymerase
• Prokaryotic Gene Regulation by Small RNAs
• Protein Domain Structure Evolution
• R
• Rad51 and Dmc1 Recombinases
• Reactive Oxygen Species
• Recombination: Mechanisms, Pathways, and Applications
• Recombineering
• Repeating Sequences in Proteins: Their Identification and Structural/Functional Implications
• Replication Origin of E. coli and the Mechanism of Initiation
• Replicative DNA Helicases and Primases
• Restriction Endonucleases
• RNA Interference
• RNA Quality Control
• RNA-Induced Chromatin Remodeling
• Rolling Circle Replicating Plasmids
• S
• Secondary Structure
• Secondary Structure by Circular Dichroism, Experimental Assessment of
• Secondary Structure, Theoretical Aspects of
• Selection with Antibiotics
• Selectivity of Chemicals for DNA Damage
• Sequence Determination, Classic Approaches to
• Sequence Information to Assess Evolutionary Relationships
• Sequence Information to Identify Motifs
• Sequence Selectivity of DNA Damage
• Signal Recognition in Lower Organisms: Light-Induced Control of Cell Movement in the Ciliates Blepharisma and Stentor
• SIKE: Discovery, Structure, and Function
• Single-Strand Annealing
• Site-Specific Mutagenesis
• Spectroscopy of Damaged DNA
• Synthesis of Modified Oligonucleotides
• Synthetic Plasmid Biology
• T
• TANK-Binding Kinase 1 (TBK1): Structure, Function, and Regulation
• Target-Primed Mobilization Mechanisms
• Target-Site Selection
• Tertiary Structure Domains, Folds and Motifs
• Tertiary Structure, Forces Maintaining the Stability of
• Theta-Replicating Plasmids, Large
• Toll-Like Receptor 3: Structure and Function
• Toll-Like Receptors: Evolution and Structure
• Toll-Like Receptors: Pathogen Recognition and Signaling
• Topoisomerases and Cancer
• Transcription Factor Classes
• Transduction of Environmental Signals by Prokaryotic Two-Component Regulatory Systems
• Transposable Elements and Plasmid Genomes
• Transposons
• U
• Ultraviolet Light DNA Damage
• uORFs: An Unusual Cis-Element That Regulates Translation
• V
• V(D)J Recombination