Genetics and Genomics in Nursing and Health Care

Editor/Author Beery, Theresa A.
Publication Year: 2018
Publisher: F.A.Davis Company

Single-User Purchase Price: $89.95
Unlimited-User Purchase Price: Not Available
ISBN: 978-0-8036-6083-0
Category: Health & Medicine - Nursing
Image Count: 122
Book Status: Available
Table of Contents

Confidently tackle the basics of genetic inheritance, the influence of somatic and germline mutations, the multifactorial relationship of gene-environment interactions, and the foundation of ethical behavior. Everyday language makes these often-intimidating topics easy to understand, while clearly defined principles, logical explanations, illustrations, tables, and clinical examples ensure you master the material.

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Table of Contents

    • About the Authors
    • Preface
    • Reviewers
    • Acknowledgments
    • UNIT I Basic Concepts From Molecular Genetics
    • Chapter 1 DNA Structure and Function
    • Introduction
    • Genetic Biology
    • DNA
    • Chapter 2 Protein Synthesis
    • Introduction
    • Transcription
    • Translation
    • Mutations
    • Summary
    • Chapter 3 Genetic Influences on Cell Division, Cell Differentiation, and Gametogenesis
    • Introduction
    • Normal Cell Biology
    • Early Embryonic Cell Biology
    • Commitment and Differentiation
    • Gametogenesis
    • Summary
    • UNIT II Gene Expression
    • Chapter 4 Patterns of Inheritance
    • Introduction
    • Mendelian Inheritance
    • Punnett Square Analysis and Probability
    • Chromosomal Inheritance
    • Complex (Multifactorial) Disease
    • Genomic Variation Influencing Susceptibility and Resistance to Health Problems
    • Summary
    • Chapter 5 Epigenetic Influences on Gene Expression
    • Introduction
    • Microbiome
    • Epigenetics and Cancer
    • Nature and Nurture Working Together
    • The Future of Epigenetics: Are There Clinical Applications?
    • Chapter 6 Autosomal Inheritance and Disorders
    • Introduction
    • Chromosomal Inheritance
    • Common Chromosomal Disorders
    • Summary
    • Chapter 7 Sex Chromosome and Mitochondrial Inheritance and Disorders
    • Introduction
    • Extra X Chromosomes
    • Extra Y Chromosomes
    • Monosomy
    • Genotype-Phenotype Gender Mismatch
    • Fragile X Syndrome
    • Mitochondrial Gene Inheritance
    • Summary
    • Chapter 8 Family History and Pedigree Construction
    • Introduction
    • Family History
    • Pedigree Construction
    • Punnett Squares
    • Pedigree Analysis
    • Summary
    • Chapter 9 Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment
    • Introduction
    • Major and Minor Anomalies
    • Classification of Congenital Anomalies
    • Syndrome or Sequence
    • Dysmorphology Assessment
    • Assessment Through a Genetic Lens
    • Summary
    • UNIT III Genomic Health Problems Across the Life Span
    • Chapter 10 Enzyme and Collagen Disorders
    • Introduction
    • Enzyme Disorders
    • Collagen Disorders
    • Summary
    • Chapter 11 Common Childhood-Onset Genetic Disorders
    • Introduction
    • Monogenic Disorders
    • Complex Disorders
    • Summary
    • Chapter 12 Common Adult-Onset Genetic Disorders
    • Introduction
    • Monogenic Disorders
    • Complex Disorders
    • Diseases Affecting Older Adults
    • Summary
    • UNIT IV Genomic Influences on Selected Complex Health Problems
    • Chapter 13 Cardiovascular Disorders
    • Introduction
    • Atherosclerosis and Coronary Artery Disease
    • Stroke
    • Hypertension
    • Arrhythmias
    • Cardiomyopathy
    • Summary
    • Chapter 14 The Genetics of Cancer
    • Introduction
    • Benign Tumor Cells
    • Cancer Cells
    • Cancer Development
    • Summary
    • Chapter 15 Genetic Contributions to Psychiatric and Behavioral Disorders
    • Introduction
    • Genetics Applications for the Psychiatric Patient
    • Autism
    • Attention-Deficit Hyperactivity Disorder
    • Schizophrenia
    • Affective Disorders
    • Substance Use Disorders
    • Personality Disorders
    • Summary
    • UNIT V Genomics and Disease Management
    • Chapter 16 Genetic and Genomic Testing
    • Introduction
    • Genetic Testing Samples
    • Types of Genetic Tests
    • Oversight of Genetic Testing
    • Laboratory Methods Used for Genetic Testing
    • Direct-to-Consumer Genetic Testing
    • Risks and Benefits of Genetic Testing
    • Summary
    • Chapter 17 Assessing Genomic Variation in Drug Response
    • Introduction
    • Pharmacodynamics
    • Pharmacokinetics
    • Genetic/Genomic Variations
    • Clinical Applications of Pharmacogenomics
    • Genetic Testing for Drug Response
    • Summary
    • Chapter 18 Health Professionals and Genomic Care
    • Introduction
    • Genetics Professionals
    • Role of General Nurses in Genomic Care
    • Interdisciplinary Health-Care Professionals
    • Summary
    • UNIT VI Global Genomic Issues
    • Chapter 19 Financial, Ethical, Legal, and Social Considerations
    • Introduction
    • Ethical Goals of Clinical Genetics
    • Genetic Discrimination
    • Duty to Warn Versus the Right to Privacy
    • Intellectual Property Rights and Gene Patents
    • Gene Therapy
    • Summary
    • Chapter 20 Genetic and Genomic Variation
    • Introduction
    • Population Genetics
    • Race, Ethnicity, and Human Genetic Variation
    • Summary
    • Appendix A Genetics Organizations and Support Groups
    • Appendix B Selected Educational Websites
    • Glossary