Genetics and Genomics in Nursing and Health Care

Editor/Author Beery, Theresa A.
Publication Year: 2018
Publisher: F.A.Davis Company

Single-User Purchase Price: $89.95 This title is available for purchase on Credo platforms only. This is not a download.
Unlimited-User Purchase Price: Not Available
ISBN: 978-0-8036-6083-0
Category: Health & Medicine - Nursing
Image Count: 122
Book Status: Available
Table of Contents

Confidently tackle the basics of genetic inheritance, the influence of somatic and germline mutations, the multifactorial relationship of gene-environment interactions, and the foundation of ethical behavior. Everyday language makes these often-intimidating topics easy to understand, while clearly defined principles, logical explanations, illustrations, tables, and clinical examples ensure you master the material.

This book is found in the following Credo Collections:

Nursing and Allied Health Essentials Collection

About the Authors
Preface
Reviewers
Acknowledgments
UNIT I Basic Concepts From Molecular Genetics
Chapter 1 DNA Structure and Function
Introduction
Genetic Biology
DNA
Chapter 2 Protein Synthesis
Introduction
Transcription
Translation
Mutations
Summary
Chapter 3 Genetic Influences on Cell Division, Cell Differentiation, and Gametogenesis
Introduction
Normal Cell Biology
Early Embryonic Cell Biology
Commitment and Differentiation
Gametogenesis
Summary
UNIT II Gene Expression
Chapter 4 Patterns of Inheritance
Introduction
Mendelian Inheritance
Punnett Square Analysis and Probability
Chromosomal Inheritance
Complex (Multifactorial) Disease
Genomic Variation Influencing Susceptibility and Resistance to Health Problems
Summary
Chapter 5 Epigenetic Influences on Gene Expression
Introduction
Microbiome
Epigenetics and Cancer
Nature and Nurture Working Together
The Future of Epigenetics: Are There Clinical Applications?
Chapter 6 Autosomal Inheritance and Disorders
Introduction
Chromosomal Inheritance
Common Chromosomal Disorders
Summary
Chapter 7 Sex Chromosome and Mitochondrial Inheritance and Disorders
Introduction
Extra X Chromosomes
Extra Y Chromosomes
Monosomy
Genotype-Phenotype Gender Mismatch
Fragile X Syndrome
Mitochondrial Gene Inheritance
Summary
Chapter 8 Family History and Pedigree Construction
Introduction
Family History
Pedigree Construction
Punnett Squares
Pedigree Analysis
Summary
Chapter 9 Congenital Anomalies, Basic Dysmorphology, and Genetic Assessment
Introduction
Major and Minor Anomalies
Classification of Congenital Anomalies
Syndrome or Sequence
Dysmorphology Assessment
Assessment Through a Genetic Lens
Summary
UNIT III Genomic Health Problems Across the Life Span
Chapter 10 Enzyme and Collagen Disorders
Introduction
Enzyme Disorders
Collagen Disorders
Summary
Chapter 11 Common Childhood-Onset Genetic Disorders
Introduction
Monogenic Disorders
Complex Disorders
Summary
Chapter 12 Common Adult-Onset Genetic Disorders
Introduction
Monogenic Disorders
Complex Disorders
Diseases Affecting Older Adults
Summary
UNIT IV Genomic Influences on Selected Complex Health Problems
Chapter 13 Cardiovascular Disorders
Introduction
Atherosclerosis and Coronary Artery Disease
Stroke
Hypertension
Arrhythmias
Cardiomyopathy
Summary
Chapter 14 The Genetics of Cancer
Introduction
Benign Tumor Cells
Cancer Cells
Cancer Development
Summary
Chapter 15 Genetic Contributions to Psychiatric and Behavioral Disorders
Introduction
Genetics Applications for the Psychiatric Patient
Autism
Attention-Deficit Hyperactivity Disorder
Schizophrenia
Affective Disorders
Substance Use Disorders
Personality Disorders
Summary
UNIT V Genomics and Disease Management
Chapter 16 Genetic and Genomic Testing
Introduction
Genetic Testing Samples
Types of Genetic Tests
Oversight of Genetic Testing
Laboratory Methods Used for Genetic Testing
Direct-to-Consumer Genetic Testing
Risks and Benefits of Genetic Testing
Summary
Chapter 17 Assessing Genomic Variation in Drug Response
Introduction
Pharmacodynamics
Pharmacokinetics
Genetic/Genomic Variations
Clinical Applications of Pharmacogenomics
Genetic Testing for Drug Response
Summary
Chapter 18 Health Professionals and Genomic Care
Introduction
Genetics Professionals
Role of General Nurses in Genomic Care
Interdisciplinary Health-Care Professionals
Summary
UNIT VI Global Genomic Issues
Chapter 19 Financial, Ethical, Legal, and Social Considerations
Introduction
Ethical Goals of Clinical Genetics
Genetic Discrimination
Duty to Warn Versus the Right to Privacy
Intellectual Property Rights and Gene Patents
Gene Therapy
Summary
Chapter 20 Genetic and Genomic Variation
Introduction
Population Genetics
Race, Ethnicity, and Human Genetic Variation
Summary
Appendix A Genetics Organizations and Support Groups
Appendix B Selected Educational Websites
Glossary