At a Glance: Medical Pharmacology at a Glance

Editor/Author Neal, Michael J.
Publication Year: 2016
Publisher: Wiley

ISBN: 978-1-118-90240-0
Category: Health & Medicine - Pharmaceutical Science
Image Count: 199
Book Status: Pending
Predicted Release Month: March 2019
Table of Contents

Medical Pharmacology at a Glance is recognised as an excellent starting point for pharmacology study. This international best-seller is the perfect companion for all medical and health students, providing an accessible, visual overview of pharmacology.

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Table of Contents

  • Preface
  • Acknowledgements
  • Further reading
  • How to use your textbook
  • About the companion website
  • 1: Introduction: principles of drug action
  • Receptors
  • Transport systems
  • Enzymes
  • Second messengers
  • G-proteins
  • 2: Drug–receptor interactions
  • Binding of drugs to receptors
  • Antagonists
  • Receptor reserve
  • Partial agonists
  • Intrinsic efficacy
  • Bioassay
  • Binding assays
  • Localization of receptors
  • Tachyphylaxis, desensitization, tolerance and drug resistance
  • 3: Drug absorption, distribution and excretion
  • Routes of administration
  • Distribution and excretion
  • Excretion
  • 4: Drug metabolism
  • Drugs
  • Liver
  • Phase I reactions
  • Phase II reactions
  • Factors affecting drug metabolism
  • 5: Local anaesthetics
  • Na+ channels
  • Action potential
  • Mechanism of local anaesthetics
  • Chemistry
  • Unwanted effects
  • Methods of administration
  • 6: Drugs acting at the neuromuscular junction
  • Presynaptic agents
  • Competitive neuromuscular blocking drugs
  • Depolarizing neuromuscular blocking drugs
  • 7: Autonomic nervous system
  • Effects of sympathetic stimulation
  • Acetylcholine
  • 8: Autonomic drugs acting at cholinergic synapses
  • Cholinomimetics
  • Muscarinic antagonists (antimuscarinics)
  • 9: Drugs acting on the sympathetic system
  • Sympathomimetics
  • Adrenoceptor antagonists
  • 10: Ocular pharmacology
  • Glaucoma
  • Mydriatics
  • 11: Asthma, hay fever and anaphylaxis
  • Mediators
  • Bronchodilators
  • Cromoglicate
  • Corticosteroids
  • Acute severe asthma
  • Antihistamines
  • 12: Drugs acting on the gastrointestinal tract I: peptic ulcer
  • Acid secretion
  • Protective factors
  • Ulcer healing drugs
  • Antacids
  • 13: Drugs acting on the gastrointestinal tract II: motility and secretions
  • Motility stimulants
  • Laxatives
  • Antidiarrhoeal drugs
  • Drugs used in inflammatory bowel disease
  • Drugs used to dissolve gallstones
  • Pancreatic supplements
  • 14: Drugs acting on the kidney: diuretics
  • Thiazides
  • Loop diuretics
  • Potassium-sparing diuretics
  • 15: Drugs used in hypertension
  • Thiazide and other diuretics
  • β-adrenoceptor antagonists
  • Vasodilator drugs
  • Centrally acting drugs
  • Acute severe hypertension
  • 16: Drugs used in angina
  • Nitrates
  • β-Adrenoceptor antagonists
  • Calcium-channel blockers
  • Revascularization
  • 17: Antiarrhythmic drugs
  • Cardiac action potential
  • Pacemaker cells
  • Drugs used in supraventricular arrhythmias
  • Drugs effective in supraventricular and ventricular arrhythmias
  • Drugs used in ventricular arrhythmias
  • Alternatives to drugs
  • 18: Drugs used in heart failure
  • ACE inhibitors and ARBs
  • β-blockers
  • Inotropic drugs
  • Sympathomimetic agents
  • 19: Drugs used to affect blood coagulation
  • Anticoagulants
  • Antiplatelet drugs
  • Fibrinolytic drugs (thrombolytics)
  • 20: Lipid-lowering drugs
  • Lipoproteins
  • Hyperlipidaemias
  • Atherosclerosis
  • Drug combinations
  • 21: Agents used in anaemias
  • Iron
  • Iron preparations
  • Vitamin B12
  • Folic acid
  • Erythropoietin
  • 22: Central transmitter substances
  • Amino acids
  • Monoamines
  • Other transmitters/modulaters
  • 23: General anaesthetics
  • Reticular activating system (RAS)
  • Mechanism of action of anaesthetics
  • Premedication
  • Intravenous agents
  • Inhalation agents
  • 24: Anxiolytics and hypnotics
  • GABA receptors
  • Barbiturate receptor
  • Benzodiazepines
  • Antidepressants
  • Drugs acting at serotonergic (5HT) receptors
  • 25: Antiepileptic drugs
  • Causes of epilepsy
  • Mechanisms of action of anticonvulsants
  • Drugs used in partial and generalized tonic–clonic (grand mal) seizures
  • Drugs used to treat absences (petit mal)
  • Drugs effective in tonic–clonic (grand mal) and absence (petit mal) seizures
  • Drug withdrawal
  • Pregnancy
  • 26: Drugs used in Parkinson's disease
  • Aetiology
  • Dopaminergic drugs
  • Dopamine agonists
  • Drugs causing dopamine release
  • MAOB and COMT inhibitors
  • Antimuscarinics
  • 27: Antipsychotic drugs (neuroleptics)
  • Dopamine receptors
  • Chemical classification
  • Depot preparations
  • 28: Drugs used in affective disorders: antidepressants
  • Monoamine theory of depression
  • Mechanism of action of antidepressants
  • Drugs that inhibit amine uptake
  • Receptor blockers
  • Monoamine oxidase inhibitors
  • Mechanism of action
  • 29: Opioid analgesics
  • Strong opioid analgesics
  • Weak opioid analgesics
  • 30: Drugs used in nausea and vertigo (antiemetics)
  • Drug-induced vomiting
  • Motion sickness
  • Vestibular disease
  • Pregnancy
  • 31: Drug misuse and dependence
  • Central stimulants
  • Opioids
  • Hallucinogens (psychedelics)
  • General depressants
  • Tobacco
  • 32: Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Mechanisms of action
  • Adverse effects
  • Other NSAIDs
  • Gout
  • 33: Corticosteroids
  • Glucocorticoids
  • Mineralocorticoids
  • 34: Sex hormones and drugs
  • Infertility
  • Testosterone
  • Oestrogens
  • Progestogens
  • Oral contraceptives
  • 35: Thyroid and antithyroid drugs
  • Hyperthyroidism (thyrotoxicosis)
  • Antithyroid drugs
  • Hypothyroidism
  • Replacement therapy
  • 36: Antidiabetic agents
  • Insulin release
  • Insulin preparations
  • Adverse effects
  • Insulin regimens
  • Oral antidiabetic drugs
  • 37: Antibacterial drugs that inhibit nucleic acid synthesis: sulphonamides, trimethoprim, quinolones and nitroimidazoles
  • Selective toxicity
  • Sulphonamides
  • Quinolones
  • 5-Nitroimidazoles
  • 38: Antibacterial drugs that inhibit cell wall synthesis: penicillins, cephalosporins and vancomycin
  • Penicillins
  • Cephalosporins
  • Other β-lactam antibiotics
  • Vancomycin
  • 39: Antibacterial drugs that inhibit protein synthesis: aminoglycosides, tetracyclines, macrolides and chloramphenicol
  • Aminoglycosides
  • Macrolides
  • Tetracyclines
  • Chloramphenicol
  • Streptogramins
  • 40: Antifungal drugs
  • Fungal infections
  • Polyenes
  • Flucytosine
  • Imidazoles
  • Triazoles
  • Echinocandins
  • 41: Antiviral drugs
  • Drugs that prevent the virus entering or leaving the host cells
  • Drugs that inhibit viral DNA polymerase
  • Drugs that inhibit viral reverse transcriptase
  • 42: Drugs acting on parasites I: helminths (worms)
  • Nematodes (roundworms)
  • Trematodes (flukes)
  • Cestodes (tapeworms)
  • Anthelmintics
  • 43: Drugs acting on parasites II: protozoa
  • Blood schizonticides (slow-acting)
  • Blood schizonticides (rapid-acting)
  • Tissue schizonticide
  • Other protozoal diseases
  • 44: Drugs used in cancer
  • Alkylating agents
  • Cytotoxic antibiotics
  • Vinca alkaloids and taxanes
  • Antimetabolites
  • Monoclonal antibodies
  • Hormones and hormone antagonists
  • 45: Immunosuppressants and antirheumatoid drugs
  • Corticosteroids
  • Antiproliferative drugs
  • Calcineurin inhibitors
  • Monoclonal antibodies
  • Disease-modifying antirheumatoid drugs (DMARDs)
  • Anticytokine drugs
  • 46: Poisoning
  • Reduction of absorption
  • Enhancement of elimination
  • Aspirin
  • Paracetamol
  • Opioids
  • Tricyclic antidepressants
  • 47: Adverse drug reactions
  • Drug interactions
  • Drug allergy
  • Teratogenesis
  • Carcinogenesis
  • Case studies and questions
  • Answers