Based on actual cases drawn from the extensive breast pathology consultation practice at Vanderbilt University Medical Center, Breast Pathology covers the full classification of breast tumors and focuses on especially challenging differential diagnoses or unusual and problematic morphologic presentations.

Table of Contents

• Series Foreword
• Foreword
• Preface
• 1. Alterations of Enlarged Lobular Units
• Preface
• 1.1 Enlarged Lobular Unit With Apocrine Change
• 1.2 Columnar Cell Lesions Without Atypia
• 1.3 Columnar Cell Lesions With Atypia
• 1.4 Secretory Change
• 2. Epithelial Proliferative Lesions
• Introduction
• 2.1 Hyperplasia Without Atypia, Usual and Florid Patterns
• 2.2 Usual Hyperplasia Without Atypia, “Gynecomastoid Pattern”
• 2.3 Usual Hyperplasia Without Atypia, Compact Pattern
• 2.4 Papillary Apocrine Change
• 2.5 Usual Hyperplasia With Prominent Myoepithelial Cells
• 2.6 Usual Hyperplasia With Clear Cells
• 2.7 Atypical Ductal Hyperplasia, Cribriform Pattern
• 2.8 Collagenous Spherulosis
• 2.9 Atypical Ductal Hyperplasia, Solid Pattern
• 2.10 Atypical Ductal Hyperplasia, Micropapillary Pattern
• 2.11 Atypical Ductal Hyperplasia With Apocrine Cytology
• 2.12 Hypersecretory Hyperplasia
• 2.13 Atypical Ductal Hyperplasia in a Background of Hypersecretory Hyperplasia
• 2.14 Florid Hyperplasia Involving a Papilloma
• 2.15 Cells of Atypical Lobular Hyperplasia Admixed With Florid Hyperplasia, Involving an Intraductal Papilloma
• 2.16 Collagenous Spherulosis Involving Micropapillomas
• 2.17 Papilloma Involved by Atypical Ductal Hyperplasia
• 2.18 Nipple Adenoma
• 2.19 Mucocele-Like Lesion
• 2.20 Mucocele-Like Lesion With Atypical Ductal Hyperplasia
• 3. Ductal Carcinoma In Situ, Special Considerations
• Introduction
• 3.1 Ductal Carcinoma In Situ, Low Grade, Minimal Example
• 3.2 Ductal Carcinoma In Situ, Solid Pattern Mimicking LCIS
• 3.3 Ductal Carcinoma In Situ, With Lobular Cytology
• 3.4 Spindle Cell Pattern Ductal Carcinoma
• 3.5 Ductal Carcinoma In Situ With Florid-Like Pattern
• 3.6 Ductal Carcinoma In Situ With Biphasic Pattern
• 3.7 Apocrine Ductal Carcinoma In Situ
• 3.8 Micropapillary Ductal Carcinoma In Situ
• 3.9 Ductal Carcinoma In Situ Arising in a Background of Hypersecretory Hyperplasia
• 3.10 Ductal Carcinoma In Situ Involving Sclerosing Adenosis
• 3.11 Displaced Epithelial Elements After Biopsy of Ductal Carcinoma In Situ
• 3.12 Invasive Carcinoma Associated With Ductal Carcinoma In Situ
• 3.13 Encysted Noninvasive Papillary Carcinoma
• 3.14 Ductal Carcinoma In Situ Involving a Papilloma With Areas of Pseudoinvasion
• 3.15 Paget's Disease of the Nipple
• 3.16 Toker Cells
• 3.17 Ductal Carcinoma In Situ With Tall Cell Pattern, Involving Papillomas
• 3.18 Secretory Ductal Carcinoma In Situ
• 3.19 Pagetoid Pattern Ductal Carcinoma In Situ
• 3.20 Radiation Change Mimicking Ductal Carcinoma In Situ
• 4. Lobular Neoplasia
• Introduction
• 4.1 Atypical Lobular Hyperplasia With Involvement of Ducts
• 4.2 Classic Lobular Carcinoma In Situ
• 4.3 Lobular Carcinoma In Situ Involving a Fibroadenoma and an Adjacent Lobular Unit
• 5. Sclerosing and Adenotic Lesions
• Introduction
• 5.1 Nodular Apocrine Sclerosing Adenosis
• 5.2 Sclerosed Adenotic Intraductal Papilloma
• 5.3 Adenomyoepithelioma
• 5.4 Radial Scar
• 5.5 Atypical Lobular Hyperplasia Involving Sclerosing Adenosis Associated With a Radial Scar
• 5.6 Microglandular Adenosis
• 5.7 Atypical Microglandular Adenosis
• 6. Fibroepithelial Lesions
• Introduction
• 6.1 Cellular Fibroadenoma
• 6.2 Atypical Ductal Hyperplasia Involving a Fibroadenoma
• 6.3 Atypical Lobular Hyperplasia Involving a Fibroadenoma
• 6.4 Benign Phyllodes Tumor
• 6.5 Borderline Phyllodes Tumor
• 6.6 Malignant Phyllodes Tumor
• 6.7 Hamartoma
• 7. Reactive and Benign Stromal Lesions
• Introduction
• 7.1 Pseudoangiomatous Stromal Hyperplasia
• 7.2 Reactive Spindle Cell Nodule
• 7.3 Nodular Fasciitis
• 7.4 Cellular Myofibroblastoma
• 7.5 Epithelioid Myofibroblastoma
• 7.6 Fibromatosis
• 7.7 Sclerosing Lymphocytic Lobulitis
• 8. Special Type Carcinomas
• Introduction
• 8.1 Tubular Carcinoma
• 8.2 Invasive Cribriform Carcinoma
• 8.3 Mucinous Carcinoma
• 8.4 Invasive Lobular Carcinoma
• 8.5 Secretory Carcinoma
• 8.6 Adenoid Cystic Carcinoma
• 8.7 Low Grade Fibromatosis-Like Metaplastic Carcinoma
• 8.8 Low Grade Adenosquamous Carcinoma
• 9. Invasive Carcinomas, Special Considerations
• Introduction
• 9.1 Invasive Micropapillary Features
• 9.2 Retraction Artifact
• 9.3 Invasive Carcinoma With Apocrine Differentiation
• 9.4 Invasive Carcinoma With Medullary Features
• 9.5 Invasive Carcinoma With Neuroendocrine Differentiation
• 9.6 Solid Pattern Invasive Carcinoma Mimicking Ductal Carcinoma In Situ
• 9.7 Lymphovascular Invasion Mimicking Ductal Carcinoma In Situ
• 9.8 Invasive Mammary Carcinoma in a Background of Microglandular Adenosis
• 9.9 Entrapped Squamous Morules Within a Previous Biopsy Site Reaction
• 10. Sentinel Lymph Nodes
• Introduction
• 10.1 Benign Transport
• 10.2 Isolated Tumor Cell Clusters
• 10.3 Micrometastasis
• 10.4 Capsular Lymphatic Involvement
• 10.5 Benign Glandular Inclusion
• 10.6 Metastatic Lobular Carcinoma
• 11. The Male Breast
• Introduction
• 11.1 Gynecomastia, Proliferative Phase
• 11.2 Atypical Ductal Hyperplasia Arising in the Setting of Gynecomastia
• 11.3 Ductal Carcinoma In Situ
• 11.4 Ductal Carcinoma In Situ Involving a Papilloma
• 12. Vascular Lesions of the Breast
• Introduction
• 12.1 Perilobular Capillary Hemangioma
• 12.2 Angiolipoma
• 12.3 Atypical Vascular Lesion
• 12.4 Angiosarcoma
• 12.5 Epithelioid Angiosarcoma